Solenne
Cognitive Performance Formula for the Menopausal Brain
Your brain isn't broken. It's running on less fuel. Solenne is the only formula built to fix that.
Ten clinically dosed ingredients. Six coordinated pathways. Results most women notice on day one.
Contains genistein, a phytoestrogen. If you are on HRT, consult your doctor before use.
Cognitive Performance Formula for the Menopausal Brain
Your brain isn't broken. It's running on less fuel. Solenne is the only formula built to fix that.
Not a wellness supplement.
A cognitive performance formula.
Your brain fog has a name. It's the Brain Brownout: the measurable drop in brain energy that happens when estrogen declines during menopause. Not stress. Not aging. A fuel problem.
Most products in this space chase symptoms. Hot flashes. Night sweats. The visible and easy-to-describe. Solenne does something different: it targets the neurological root cause, across six coordinated biological pathways, with ten ingredients included at clinical doses for documented reasons.
Zero fillers. Zero marketing fluff. This is the formula that should
have existed twenty years ago.
Six pathways. One formula.
Every pathway targets a distinct mechanism in the brain brownout cascade. Together, they rebuild the conditions your brain needs to perform.
Every ingredient.
Every dose. Fully transparent.
No proprietary blends. No underdosed inclusions. Every ingredient in Solenne is named, dosed, and explained. Serving size: 3 capsules.
Citicoline
250 mg
Acetylcholine support; Brain cell membrane health
Rebuilds the neurotransmitter responsible for memory and word retrieval. Works within hours on day one; structural benefits build over 2 to 4 weeks.
Lion's Mane
250 mg · 30% extract
Cognitive Resilience; Nerve Growth Factor support
Stimulates the growth proteins that build and maintain neural infrastructure. The long-term structural backbone of the formula; full effect at weeks 8 to 12.
Ashwagandha KSM-66
300 mg · 5% withanolides
Stress Management; Cortisol Reduction; Hormonal Support
Reduces cortisol and the FSH spike that drives neurological stress during menopause. Also supports the body's own estrogen production over 8 to 12 weeks of daily consistent use.
Genistein - 60 mg
(from Sophora japonica - not soy)
Pathway: Brain-Targeted Estrogen Support
Estrogen acts like a master power switch for the brain, helping your cells turn food into the energy you need to think. When estrogen drops, the power grid falters, leaving your brain struggling to light up fully. Genistein is a natural plant compound that steps in to mimic estrogen right where your brain needs it most. It hooks directly into the brain’s receptors to help pick up the slack and keep the lights on. For women not taking HRT, this provides a targeted way to maintain mental stamina, clarity, and focus without having to consume soy.
Riboflavin - 400 mg
(Vitamin B2)
Pathway: Brain Energy & Cellular Stamina
Riboflavin acts like a vital spark plug for your cells, helping your brain turn fuel into clean mental energy. When hormone levels shift and brain energy drops, your neural system can become overly sensitive, triggering intense head tension and brain fog. At a heavy-duty, clinically backed 400 mg dose, Riboflavin recharges your brain's internal power plants and stabilizes the system, protecting your mind against the pressure and afternoon slumps driven by an energy deficit.
Saffron - 30 mg
Pathway: Mood, Sleep & Sharpness
Saffron is far more than a calming botanical; it is a high-performance brain optimizer. It works by keeping your feel-good chemical messengers active for longer, which directly cuts through the emotional exhaustion and memory slips that come with menopause. At a premium, clinically validated 30 mg dose, it acts like a steady anchor for your nervous system, keeping your mood resilient and your focus sharp throughout the day.
L-Theanine - 100 mg
Pathway: Calm Focus & Stress Resilience
True focus isn't about revving your brain up; it's about quieting the noise. L-Theanine guides your mind into what scientists call a state of "relaxed alertness," the same mental space you enter during deep creative flow. It gently dials down the internal static and racing thoughts triggered by shifting hormones, allowing you to think clearly, stay present, and lock into your work without a single drop of drowsiness.
DIM (Diindolylmethane) - 100 mg
Pathway: Hormone Clearance & Cellular Balance
If Genistein's job is to turn the brain's power grid back on, DIM’s job is to manage the clean-up crew. It works at a cellular level like a traffic controller, directing your body to break down and clear out used estrogen through the safest, most efficient pathways. By smoothing out how your body processes these hormones, it helps prevent the internal spikes and chaotic fluctuations that cause mental friction during the menopausal transition.
Biotin - 30 mcg
Pathway: Energy Production & Brain Processing Speed
Your brain cells can’t use raw fuel on their own; they need a spark to unlock it. Biotin is a critical helper molecule that allows your cells to convert fats and proteins into usable brain energy. By driving this internal metabolic engine, it ensures your brain has a steady, unbroken supply of power, allowing Solenne to give you the underlying stamina required to keep your mind sharp under pressure.
Zinc (as Zinc Bisglycinate) - 10 mg
Pathway: Memory Recall & Neuro-Resilience
Zinc is the master key for the hippocampus, the exact region of the brain responsible for creating new memories and retrieving old ones. It actively maintains the communication channels that allow your brain to file away information smoothly. Solenne uses Zinc Bisglycinate, the most highly absorbable form available, ensuring this critical memory center gets the exact fuel it needs to prevent daily slip-ups and keep your recall lightning-fast.
Most women notice a change within the first week. The full picture takes 90 days.

How to take Solenne
Take 3 capsules every morning with a fat-containing breakfast (eggs, avocado, or nuts work well).
Morning timing matters: Citicoline increases brain energy and dopamine; taking it at night can disrupt sleep. Saffron's active compounds are most effective when taken in the morning.
Consistency is everything. Take it at the same time every day and give the formula the runway it deserves.
Most women notice a change on day one. Full effect builds over 90 days of consistent daily use.
Storage
Store in a cool, dry place away from direct sunlight and excessive heat. Keep below 25°C. Tighten the cap after each use. Keep out of reach of children. Do not use if the seal is damaged or missing.
The supplement built for your brain. Not theirs.
Most menopause supplements were designed for hot flashes. Solenne was designed for the symptom nobody talks about. Here is the difference.
* Comparison based on publicly available information about commonly available menopause supplement formulations. No specific brand has been named.
Testimonials
From women who refused to accept the fog.
"I'd been misattributing it to burnout for almost two years. Within six weeks on Solenne, I was holding threads again in meetings I used to dread."
"My doctor told me I was fine. My brain was telling me something very different. Solenne was the first thing that made sense of what I was experiencing."
"I thought the sharpness was just gone. It wasn't. I just needed the right support."
Frequently Asked Questions
Solenne contains genistein, a phytoestrogen that acts on estrogen receptors. If you are currently taking HRT, consult your prescribing doctor before use, as genistein may interact with your HRT. A genistein-free version is being explored for a future release.
Most menopause supplements target hot flashes. Solenne targets the cognitive symptoms: brain fog, word loss, and mental fatigue. Every ingredient addresses a specific, documented mechanism in the brain brownout cascade. No fillers, no underdosed inclusions, no proprietary blend concealment.
Day 1: Calm focus from L-Theanine and Citicoline within 1 to 5 hours.
Week 1: Sleep quality and stress reactivity begin to shift.
Weeks 2 to 4: Clearer thinking, steadier mood, easier word retrieval.
Weeks 4 to 8: Peak clinical window across the full formula.
Month 3+: Neuroprotective and hormonal benefits continue to build.
We recommend a minimum 90-day consistent use commitment.
Yes. The Brain Brownout model is grounded in published PET neuroimaging research documenting measurable drops in brain glucose metabolism during menopause. Every ingredient is backed by peer-reviewed clinical literature. Sources are published on The Science page. Solenne is manufactured at an FDA-registered, NSF GMP-certified, cGMP-compliant facility.
Because the formula is a premium formula. KSM-66 ashwagandha (5% withanolides), Lion's Mane at 30% polysaccharides, Saffron at 2% Safranals and 4-6% Crocins, and clinical-grade ingredients at therapeutic doses cost significantly more than standard supplement formulations. You are paying for clinical integrity, not branding.
Yes. All active ingredients in Solenne are plant-derived. The formula contains no animal derivatives, no gelatin, and no animal-based excipients.
We stand behind Solenne completely. If you are not satisfied within 30 days of your first order, contact us, and we will make it right.
Don't let the fog define this chapter.
Don't let the fog define this chapter.
Start with one month. Give your brain the science it's been waiting for.
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