-
75%
of women in menopause experience cognitive symptoms
-
60%
say it affects their work performance
-
1.6bn
women worldwide will go through menopause
-
0
major brands currently own the cognitive performance space in menopause
Don't let the fog define this chapter.
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Your Edge
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Clinically dosed | Transparent formula | Science-backed | Made in the USA
WE SEE YOU.
You're not imagining it.
And you're not alone.
You've spent twenty years being the sharpest person in the room. Now you lose a word mid-sentence. You re-read the same email four times and still can't hold the thread. You blank on the name of a colleague you've known for a decade, then spend the rest of the meeting wondering if anyone noticed.
You aren't losing your edge, you’re navigating a major biological transition. That’s why we formulated Solenne to protect your focus and keep your mind sharp.
The science behind the symptom
Your brain isn't broken.
It's running on reduced power.
A new framework for understanding what menopause actually does to the female brain.
Meet the brain brownout
Not a blackout. Not a breakdown. A brownout. This is when the lights flicker but don't go out. When the system is intact but running below capacity. That's precisely what happens to the menopausal brain, and it has a name now.
The estrogen-glucose connection (and the FSH spike)
Estrogen isn't just a reproductive hormone; it drives energy production in the brain. When estrogen levels decline in perimenopause, energy production in the key areas of the brain, the hippocampus and prefrontal cortex, drops measurably. But that is only half the story. In response to this decline, the brain overproduces Follicle-Stimulating Hormone (FSH). This massive FSH spike crosses directly into those key areas triggering cellular stress that further stalls performance. Brain imaging confirms it: this dual hormonal shift disrupts glucose uptake and energy production precisely when professional demands peak. Solenne is formulated to bypass this metabolic friction, supporting optimal brain energy to keep you sharp in the boardroom, the courtroom, or the clinic.
An energy deficit, not an intelligence deficit
Your brain hasn't changed. Your brain's fuel supply has. The neural pathways are there. The capability is there. What's missing is the metabolic support to run them at full capacity. Solenne was formulated specifically to address that gap: six coordinated pathways, one formula.
Meet the brain brownout
Not a blackout. Not a breakdown. A brownout. This is when the lights flicker but don't go out. When the system is intact but running below capacity. That's precisely what happens to the menopausal brain, and it has a name now.
The estrogen-glucose connection (and the FSH spike)
Estrogen isn't just a reproductive hormone; it drives energy production in the brain. When estrogen levels decline in perimenopause, energy production in the key areas of the brain, the hippocampus and prefrontal cortex, drops measurably. But that is only half the story. In response to this decline, the brain overproduces Follicle-Stimulating Hormone (FSH). This massive FSH spike crosses directly into those key areas triggering cellular stress that further stalls performance. Brain imaging confirms it: this dual hormonal shift disrupts glucose uptake and energy production precisely when professional demands peak. Solenne is formulated to bypass this metabolic friction, supporting optimal brain energy to keep you sharp in the boardroom, the courtroom, or the clinic.
An energy deficit, not an intelligence deficit
Your brain hasn't changed. Your brain's fuel supply has. The neural pathways are there. The capability is there. What's missing is the metabolic support to run them at full capacity. Solenne was formulated specifically to address that gap: six coordinated pathways, one formula.
The activity of the enzymes that manufacture this essential "smart" neurotransmitter, acetylcholine, drops by up to 50% in the memory and decision-making centers.
HOW SOLENNE WORKS
Six pathways. One formula.
No single ingredient fixes the menopausal brain. Solenne was built around six coordinated mechanisms, each targeting a distinct part of the cognitive decline cascade. Ten ingredients. Six pathways. One formula designed from the ground up for the brain you depend on.
Genistein + DIM + Ashwagandha
Riboflavin + Biotin
Citicoline
Ashwagandha KSM-66 + L-Theanine
Lion's Mane + Zinc Bisglycinate + Saffron
Saffron
Don't let the fog define this chapter.
One formula. Three ways to commit to your edge.
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Clinically dosed | Transparent formula | Science-backed | Made in the USA
WHAT'S INSIDE
Formulated for
the menopausal brain.
Every ingredient earns its place.
Solenne contains no fillers, no proprietary blends, no underdosed gestures at science. Each ingredient is clinically selected at a confirmed dose to address a specific mechanism in the brain brownout model.
Citicoline - 250 mg
Pathway: Acetylcholine Production & Cellular Repair
When word retrieval slows down, or you walk into a room and forget why, your brain is often signaling a drop in acetylcholine. Menopause can cut the activity of the enzymes that make this essential neurotransmitter by up to 50%, forcing your processing speed to lag. Citicoline counters this by delivering the raw materials your brain needs to support its cell membranes and ramp up acetylcholine production. It helps move your brain back into real-time speed.
Lion's Mane
(30% Polysaccharide Extract)
Pathway: Cognitive Longevity & Mental Agility
A changing brain doesn't mean a compromised one. Lion's Mane stimulates Nerve Growth Factor (NGF), the primary protein your brain uses to build new cellular pathways. Instead of just trying to hold onto your current baseline, this gives your brain the raw environmental support it needs to stay agile, absorb new information, and adapt effortlessly to complex demands.
Ashwagandha KSM-66 - 300 mg
(standardized to 5% withanolides)
Pathway: Stress & Hormone Balance
Menopause triggers a double-spike in both cortisol (the stress hormone) and FSH. This hormonal surge drains your mental stamina and makes it harder to focus under pressure. KSM-66 is a heavily researched plant extract that works right at the source to calm the nervous system, balance cortisol, and smooth out the daily friction of the menopausal transition.
Genistein - 60 mg
(from Sophora japonica - not soy)
Pathway: Brain-Targeted Estrogen Support
Estrogen acts like a master power switch for the brain, helping your cells turn food into the energy you need to think. When estrogen drops, the power grid falters, leaving your brain struggling to light up fully. Genistein is a natural plant compound that steps in to mimic estrogen right where your brain needs it most. It hooks directly into the brain’s receptors to help pick up the slack and keep the lights on. For women not taking HRT, this provides a targeted way to maintain mental stamina, clarity, and focus without having to consume soy.
Riboflavin - 400 mg
(Vitamin B2)
Pathway: Brain Energy & Cellular Stamina
Riboflavin acts like a vital spark plug for your cells, helping your brain turn fuel into clean mental energy. When hormone levels shift and brain energy drops, your neural system can become overly sensitive, triggering intense head tension and brain fog. At a heavy-duty, clinically backed 400 mg dose, Riboflavin recharges your brain's internal power plants and stabilizes the system, protecting your mind against the pressure and afternoon slumps driven by an energy deficit.
Saffron - 30 mg
Pathway: Mood, Sleep & Sharpness
Saffron is far more than a calming botanical; it is a high-performance brain optimizer. It works by keeping your feel-good chemical messengers active for longer, which directly cuts through the emotional exhaustion and memory slips that come with menopause. At a premium, clinically validated 30 mg dose, it acts like a steady anchor for your nervous system, keeping your mood resilient and your focus sharp throughout the day.
L-Theanine - 100 mg
Pathway: Calm Focus & Stress Resilience
True focus isn't about revving your brain up; it's about quieting the noise. L-Theanine guides your mind into what scientists call a state of "relaxed alertness," the same mental space you enter during deep creative flow. It gently dials down the internal static and racing thoughts triggered by shifting hormones, allowing you to think clearly, stay present, and lock into your work without a single drop of drowsiness.
DIM (Diindolylmethane) - 100 mg
Pathway: Hormone Clearance & Cellular Balance
If Genistein's job is to turn the brain's power grid back on, DIM’s job is to manage the clean-up crew. It works at a cellular level like a traffic controller, directing your body to break down and clear out used estrogen through the safest, most efficient pathways. By smoothing out how your body processes these hormones, it helps prevent the internal spikes and chaotic fluctuations that cause mental friction during the menopausal transition.
Biotin - 30 mcg
Pathway: Energy Production & Brain Processing Speed
Your brain cells can’t use raw fuel on their own; they need a spark to unlock it. Biotin is a critical helper molecule that allows your cells to convert fats and proteins into usable brain energy. By driving this internal metabolic engine, it ensures your brain has a steady, unbroken supply of power, allowing Solenne to give you the underlying stamina required to keep your mind sharp under pressure.
Zinc (as Zinc Bisglycinate) - 10 mg
Pathway: Memory Recall & Neuro-Resilience
Zinc is the master key for the hippocampus, the exact region of the brain responsible for creating new memories and retrieving old ones. It actively maintains the communication channels that allow your brain to file away information smoothly. Solenne uses Zinc Bisglycinate, the most highly absorbable form available, ensuring this critical memory center gets the exact fuel it needs to prevent daily slip-ups and keep your recall lightning-fast.
Most women notice a change within the first week. The full picture takes 90 days.
Testimonials
From women who refused to accept the fog.
"I'd been misattributing it to burnout for almost two years. Within six weeks on Solenne, I was holding threads again in meetings I used to dread."
"My doctor told me I was fine. My brain was telling me something very different. Solenne was the first thing that made sense of what I was experiencing."
"I thought the sharpness was just gone. It wasn't. I just needed the right support."
Built for the woman the industry overlooked.
Founder Claudia Armstead spent seven years in the nutraceutical industry watching science evolve rapidly, while one group remained consistently overlooked: the woman at the peak of her power. When she watched her mother, a woman who had spent decades leading with a razor-sharp intellect, start to doubt herself during menopause, she knew the industry had failed to answer the most important question in women's cognitive health.
Solenne was her answer. Not another supplement. Protection for women who aren't finished yet.
The name reflects the mission: Solemn Brightness. A spark that should never go out, but shine brighter.
Don't let the fog define this chapter.
You built your career on the strength of your mind. That mind is still there. It just needs the right support to perform.
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Clinically dosed | Transparent formula | Science-backed | Made in the USA
Reclaim your edge
Understand your brain
Because you're not looking for supplements.
You're looking for answers.
A new framework for understanding what menopause actually does to the female brain.